Description

Methyl 5-Bromo-2-Iodobenzoate is a high-purity, multi-halogenated aromatic ester building block of significant importance in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and R&D teams in the life sciences, material science, and fine chemical industries who require reliable, high-quality intermediates for coupling reactions and derivatization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex biaryl or heterocyclic structures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its aromatic and halogenated nature.
• Cross-Coupling Reactions: An excellent substrate for Suzuki-Miyaura, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology: Used as a probe or tagging reagent in bioconjugation and the study of biological pathways.

Basic Information

Product Name	Methyl 5-Bromo-2-Iodobenzoate
CAS No.	181765-86-6
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	Benzoic acid, 5-bromo-2-iodo-, methyl ester; Methyl 5-bromo-2-iodobenzoate; 5-Bromo-2-iodobenzoic acid methyl ester; 2-Iodo-5-bromobenzoic acid methyl ester; Methyl 2-iodo-5-bromobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-Iodobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.