Description

(5-Bromo-Pyridin-2-Yl)-Phenyl-Methanol is a high-purity brominated pyridine derivative, a crucial chiral building block in advanced organic synthesis. Its value lies in its versatile reactivity, particularly for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel small-molecule drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromopyridine moiety offers specific bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials and functionalized polymers requiring precise bromine substitution patterns.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and Industrial R&D: Used in methodological studies and for exploring new carbon-carbon and carbon-heteroatom bond-forming reactions.

Basic Information

Product Name	(5-Bromo-Pyridin-2-Yl)-Phenyl-Methanol
CAS No.	181647-50-7
Molecular Formula	C12H10BrNO
Molecular Weight	264.12 g/mol
Synonyms	α-Phenyl-5-bromopyridin-2-ylmethanol; (5-Bromo-2-pyridinyl)phenylmethanol; 2-Pyridinemethanol, 5-bromo-α-phenyl-; 5-Bromo-α-phenyl-2-pyridinemethanol; Benzhydrol, 5-bromo-2-pyridinyl-; (5-Bromopyridin-2-yl)(phenyl)methanol; 181647-50-7; (5-Bromo-2-pyridyl)phenylmethanol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to cGMP principles for manufacturing and quality management where applicable, supporting our commitment to supply reliability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.