Description

Zinquin Ethyl Ester CAS NO 181530-09-6 is a highly specific, cell-permeable fluorescent probe designed for the selective detection and quantification of labile intracellular zinc (Zn²⁺). This compound matters because it provides researchers with a critical tool for visualizing zinc dynamics in live cells, a key signaling ion involved in numerous physiological and pathological processes. It is essential for life science researchers, pharmaceutical developers, and diagnostic manufacturers working in neurobiology, immunology, and metabolic disease research.

Application

• Live-Cell Zinc Imaging: Real-time visualization and tracking of labile zinc pools in neuronal, immune, and pancreatic cells.
• Neuroscience Research: Studying the role of synaptic zinc in neurotransmission, learning, memory, and neurodegenerative conditions.
• Immunology Studies: Investigating zinc flux as a signaling event in immune cell activation and function.
• Diabetes & Metabolic Research: Monitoring zinc secretion and homeostasis in insulin-producing pancreatic beta cells.
• Drug Discovery Screening: Serving as a key reagent in assays to identify compounds that modulate zinc transporter activity or cellular zinc homeostasis.
• Diagnostic Assay Development: Acting as a core component in the development of fluorescent-based diagnostic kits for zinc-related disorders.

Basic Information

Product Name	Zinquin Ethyl Ester
CAS No.	181530-09-6
Molecular Formula	C₂₀H₁₈N₂O₃S
Molecular Weight	366.44 g/mol
Synonyms	Zinquin ethyl ester; Zinquin Ester; Ethyl [2-methyl-8-(4-toluenesulfonamido)-6-quinolyloxy]acetate; TSQ derivative; Zinc indicator Zinquin Ester; N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide ethyl ester; Zinquin fluorescent probe; Intracellular zinc probe
EINECS	Contact for details

Quality Control

Our Zinquin Ethyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive biological assays. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing purity, identity, and performance data are provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. Solutions prepared in DMSO should be aliquoted and stored at -20°C or -80°C, protected from light, and used promptly.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Functional Performance (Fluorescence)	Exhibits characteristic zinc-dependent fluorescence enhancement

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.