Description

2-(2,5-Dichloro-Phenylsulfanyl)-Nicotinic Acid is a high-purity organic intermediate featuring a nicotinic acid core substituted with a dichlorophenylthio group. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, enabling the introduction of specific halogenated aromatic motifs. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the dichlorophenyl moiety.
• Material Science Research: Used in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular scaffold.

Basic Information

Product Name	2-(2,5-Dichloro-Phenylsulfanyl)-Nicotinic Acid
CAS No.	181527-55-9
Molecular Formula	C12H7Cl2NO2S
Molecular Weight	300.16 g/mol
Synonyms	2-[(2,5-Dichlorophenyl)thio]nicotinic acid; 2-(2,5-Dichlorophenylthio)nicotinic acid; Nicotinic acid, 2-[(2,5-dichlorophenyl)thio]-; 2-(2,5-Dichloro-benzenesulfanyl)-pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-[(2,5-dichlorophenyl)thio]-; 181527-55-9; 2-(2,5-Dichlorophenylsulfanyl)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dichloro-Phenylsulfanyl)-Nicotinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.