Description

(E)-tert-Butyl 3-(Pyridin-2-Yl)Acrylate is a high-purity, versatile acrylate ester building block featuring a pyridine moiety. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is essential for chemists and process developers in the life sciences, agrochemical, and advanced materials sectors seeking to introduce specific functional groups and structural motifs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the pyridine ring's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Polymer Science: Incorporated as a functional monomer to impart specific chemical properties, such as adhesion or reactivity, into advanced polymer systems.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its conjugated structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.

Basic Information

Item	Detail
Product Name	(E)-tert-Butyl 3-(Pyridin-2-Yl)Acrylate
CAS No.	181517-75-9
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	tert-Butyl (2E)-3-(2-pyridinyl)-2-propenoate; (E)-3-(2-Pyridyl)acrylic acid tert-butyl ester; 2-Propenoic acid, 3-(2-pyridinyl)-, 1,1-dimethylethyl ester, (2E)-; (E)-tert-Butyl 3-(2-pyridinyl)acrylate; tert-Butyl (E)-3-(pyridin-2-yl)acrylate; (E)-3-(Pyridin-2-yl)acrylic acid tert-butyl ester; 181517-75-9; Acrylic acid, 3-(2-pyridyl)-, tert-butyl ester, (E)-
EINECS	Contact for details

Quality Control

Every batch of (E)-tert-Butyl 3-(Pyridin-2-Yl)Acrylate is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical and pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles—typically determined by HPLC, GC, NMR, and IR—is provided with each shipment to guarantee reliable and consistent performance in your synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.