Description

2-Chloro-3-Cyano-Pyridine 1-Oxide is a versatile and high-value heterocyclic building block, primarily used in advanced pharmaceutical and agrochemical synthesis. Its unique structure, featuring both chloro and cyano substituents on the pyridine N-oxide ring, makes it a critical intermediate for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce novel functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic and Industrial R&D: Used in exploratory chemistry for method development and the creation of new chemical libraries for screening.

Basic Information

Product Name	2-Chloro-3-Cyano-Pyridine 1-Oxide
CAS No.	181283-98-7
Molecular Formula	C6H3ClN2O
Molecular Weight	154.55 g/mol
Synonyms	2-Chloro-3-cyanopyridine 1-oxide; 2-Chloro-3-cyanopyridine N-oxide; 3-Cyano-2-chloropyridine 1-oxide; 2-Chloro-3-pyridinecarbonitrile 1-oxide; Pyridine, 2-chloro-3-cyano-, 1-oxide; 2-Chloronicotinonitrile 1-oxide; 181283-98-7
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Cyano-Pyridine 1-Oxide is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.