Description

Piperidin-4-Yl-Pyridin-4-Yl-Amine X 2 Hcl is a high-purity, dihydrochloride salt form of a key heterocyclic amine building block. This compound matters as a versatile and critical intermediate in modern pharmaceutical research and development, particularly for the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its bifunctional piperidine-pyridine scaffold.
• Process Chemistry & Scale-up: Serves as a starting material or intermediate in the development of robust, scalable synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Library Synthesis for High-Throughput Screening: Employed in the generation of diverse compound libraries for biological screening against novel targets.
• Ligand Synthesis: Can be utilized in the preparation of ligands for catalysis or in chemical biology probes.
• Fine Chemical Synthesis: Acts as a specialized intermediate in the custom synthesis of complex, high-value organic molecules.

Basic Information

Product Name	Piperidin-4-Yl-Pyridin-4-Yl-Amine X 2 Hcl
CAS No.	181258-50-4
Molecular Formula	C10H17Cl2N3
Molecular Weight	250.17 g/mol
Synonyms	4-[(Pyridin-4-yl)amino]piperidine dihydrochloride; 4-Pyridin-4-ylaminopiperidine dihydrochloride; 4-Amino-4'-pyridinylpiperidine dihydrochloride; 1-Piperidin-4-yl-pyridin-4-yl-amine dihydrochloride; 4-(4-Pyridinylamino)piperidine dihydrochloride; N-(Piperidin-4-yl)pyridin-4-amine dihydrochloride; 181258-50-4 (CAS)
EINECS	Contact for details

Quality Control

Our Piperidin-4-Yl-Pyridin-4-Yl-Amine X 2 Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.