Description

(Rac)-Aziridine-1,2-Dicarboxylic Acid 1-Tertbutyl Ester 2-Methyl Ester is a versatile chiral aziridine derivative, a crucial building block in advanced organic synthesis. Its value lies in providing a protected, reactive three-membered heterocyclic ring system that enables the stereoselective introduction of nitrogen and carbon functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including protease inhibitors, antibiotics, and other biologically active nitrogen-containing molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific stereochemistry for optimal activity.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands, catalysts, and auxiliaries used in enantioselective transformations.
• Peptidomimetics & Bioactive Molecule Design: The aziridine ring is a valuable scaffold for creating conformationally constrained peptide analogs and other bioactive compounds.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialized polymers with unique properties.
• Academic & R&D Laboratories: A high-purity reagent for methodological development in organic chemistry and chemical biology studies.

Basic Information

Product Name	(Rac)-Aziridine-1,2-Dicarboxylic Acid 1-Tertbutyl Ester 2-Methyl Ester
CAS No.	181212-90-8
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-2-(methoxycarbonyl)aziridine (racemic); (±)-1-(tert-Butoxycarbonyl)-2-(methoxycarbonyl)aziridine; rac-1-Boc-2-(COOMe)aziridine; Aziridine-1,2-dicarboxylic acid, 1-(1,1-dimethylethyl) 2-methyl ester; 1-tert-Butyl 2-methyl aziridine-1,2-dicarboxylate; (Rac)-1-Boc-aziridine-2-carboxylic acid methyl ester; tert-Butyl methyl aziridine-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our (Rac)-Aziridine-1,2-Dicarboxylic Acid 1-Tertbutyl Ester 2-Methyl Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral analysis, to ensure high chemical and isomeric purity suitable for demanding R&D and scale-up applications. A detailed Certificate of Analysis (COA) with full spectroscopic data is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Racemic mixture (50:50 enantiomer ratio)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.