Description

5-Chloro-3-Nitropyridine-2-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring chloro, nitro, and cyano substituents, makes it a versatile precursor for constructing complex pharmacophores and agrochemical intermediates. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, dyes, and functionalized polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and biochemical tools for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functional group manipulation.

Basic Information

Product Name	5-Chloro-3-Nitropyridine-2-Carbonitrile
CAS No.	181123-11-5
Molecular Formula	C6H2ClN3O2
Molecular Weight	183.55 g/mol
Synonyms	2-Cyano-5-chloro-3-nitropyridine; 5-Chloro-3-nitro-2-pyridinecarbonitrile; 5-Chloro-3-nitropicolinonitrile; 2-Pyridinecarbonitrile, 5-chloro-3-nitro-; 181123-11-5; 5-Chloro-3-nitropyridine-2-carbonitrile; 3-Nitro-5-chloropyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Nitropyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.