Description

2-(Trifluoromethyl)-Benzeneacetic Acid Methyl Ester is a high-purity fluorinated aromatic ester, a key building block in advanced organic synthesis. This compound is valued for its trifluoromethyl group, which imparts unique electronic and lipophilic properties to target molecules, enhancing their metabolic stability and bioavailability. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic chemicals used in display and lighting technologies.
• Advanced Material Monomers: Incorporated into polymers and specialty coatings to enhance chemical resistance, durability, and surface properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for method development and the creation of novel fluorinated compound libraries.

Basic Information

Product Name	2-(Trifluoromethyl)-Benzeneacetic Acid Methyl Ester
CAS No.	181039-97-4
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	Methyl 2-(Trifluoromethyl)phenylacetate; Methyl (2-(Trifluoromethyl)phenyl)acetate; α-(Trifluoromethyl)benzeneacetic Acid Methyl Ester; 2-(Trifluoromethyl)benzeneacetic Acid Methyl Ester; Methyl α-(Trifluoromethyl)phenylacetate; (2-(Trifluoromethyl)phenyl)acetic Acid Methyl Ester; 2-(Trifluoromethyl)phenylacetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethyl)-Benzeneacetic Acid Methyl Ester is manufactured under a strict quality management system. We employ advanced analytical techniques, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the rigorous standards required for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.