Description

Spiramilactone B CAS NO 180961-65-3 is a high-purity, specialized chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and study of novel therapeutic agents, particularly those targeting hormonal pathways. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation pharmaceuticals.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathways for novel steroid-based or hormonal active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate biological activity, receptor binding affinity, and metabolic pathways.
• Process Development: Serves as a critical material for scaling up and optimizing synthetic routes during process chemistry development.
• Academic Research: Utilized by universities and research institutes for fundamental studies in medicinal chemistry and pharmacology.

Basic Information

Product Name	Spiramilactone B
CAS No.	180961-65-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Spiramilactone B; 180961-65-3; (7α,17α)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone; Canrenone Impurity; Spironolactone Related Compound; SC-26304; 7α-Thioacetylspironolactone
EINECS	Contact for details

Quality Control

Our Spiramilactone B is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.