Description

Lasofoxifene is a third-generation selective estrogen receptor modulator (SERM) with a distinct chemical structure. This compound is valued for its targeted pharmacological profile, offering a high degree of receptor selectivity. It is primarily utilized in advanced pharmaceutical research and development, particularly for applications in oncology and metabolic bone disorders. Our supply ensures high-purity material suitable for critical development and manufacturing processes.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of prescription medications targeting estrogen receptor pathways.
• Oncology Research: Investigated for its potential role in the treatment and prevention of hormone-responsive cancers, including breast cancer.
• Osteoporosis R&D: Key compound in research programs focused on developing novel therapies for bone density preservation and fracture risk reduction.
• Preclinical & Clinical Studies: Serves as a reference standard and active agent in pharmacokinetic, pharmacodynamic, and toxicological evaluations.
• Biochemical Research: Used as a selective molecular probe to study estrogen receptor (ER) signaling mechanisms and interactions.
• GMP Manufacturing: Sourced as a high-quality starting material or intermediate for the synthesis of finished dosage forms under Good Manufacturing Practices.

Basic Information

Item	Detail
Product Name	Lasofoxifene
CAS No.	180915-85-9
Molecular Formula	C28H31F2NO3
Molecular Weight	467.55 g/mol
Synonyms	Lasofoxifene; CP-336,156; (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol; Fablyn; Beuronta; Selective Estrogen Receptor Modulator CP-336156; CP 336156
EINECS	Contact for details

Quality Control

Our Lasofoxifene is produced and tested to meet stringent quality standards appropriate for pharmaceutical research and development. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced chromatographic and spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.