Description

7-Aminopyrazolo[1,5-A]Pyrido[3,4-E]Pyrimidin-6(7H)-One is a high-purity, advanced pharmaceutical intermediate belonging to a class of fused heterocyclic compounds. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel, potent therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of small molecule drugs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing novel kinase inhibitors, which are crucial in oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used by R&D laboratories for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Tool Compound: Can be utilized in the development of biochemical probes for studying specific enzyme functions and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	7-Aminopyrazolo[1,5-A]Pyrido[3,4-E]Pyrimidin-6(7H)-One
CAS No.	180904-95-4
Molecular Formula	C9H7N5O
Molecular Weight	201.19 g/mol
Synonyms	7-Amino-6H-pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-one; 7-Amino-6-oxo-6,7-dihydropyrazolo[1,5-a]pyrido[3,4-e]pyrimidine; Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6(7H)-one, 7-amino-; 180904-95-4; 7-Aminopyrazolopyridopyrimidinone; API Intermediate 180904-95-4
EINECS	Contact for details

Quality Control

Our 7-Aminopyrazolo[1,5-A]Pyrido[3,4-E]Pyrimidin-6(7H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and pre-clinical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.