Description

2-Fluoro-6-(3-(trifluoromethyl)phenyl)pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethylphenyl group, makes it an essential intermediate for creating compounds with enhanced biological activity and material properties. This product is primarily targeted at research and development teams within the pharmaceutical, agrochemical, and materials science industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Research: Used in the synthesis of next-generation herbicides and pesticides, where the fluorine and trifluoromethyl groups can improve metabolic stability and lipophilicity.
• Ligand & Catalyst Development: Serves as a precursor for constructing sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs, due to its electron-deficient aromatic system.
• Chemical Biology Probe Synthesis: Utilized to create fluorinated analogs of bioactive molecules for mechanistic studies and target identification.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring the introduction of specific fluorinated aromatic motifs.

Basic Information

Product Name	2-Fluoro-6-(3-(trifluoromethyl)phenyl)pyridine
CAS No.	180606-19-3
Molecular Formula	C12H7F4N
Molecular Weight	241.19 g/mol
Synonyms	2-Fluoro-6-[3-(trifluoromethyl)phenyl]pyridine; 6-Fluoro-2-[3-(trifluoromethyl)phenyl]pyridine; 2-Fluoro-6-(3-trifluoromethylphenyl)pyridine; 2-Fluoro-6-(alpha,alpha,α-trifluoro-m-tolyl)pyridine; [3-(6-Fluoropyridin-2-yl)phenyl]trifluoromethane; 180606-19-3; 2-Pyridine, 2-fluoro-6-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(3-(trifluoromethyl)phenyl)pyridine is produced and tested under strict quality management systems. We guarantee high purity and consistency, with standard analytical controls including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.