Description

2-Bromo-6-(3-(trifluoromethyl)phenyl)pyridine is a high-value, multi-functional heterocyclic building block characterized by its bromo and trifluoromethylphenyl substituents. This compound is essential for facilitating advanced cross-coupling reactions, enabling the rapid synthesis of complex molecular architectures in medicinal chemistry and materials science. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials due to its rigid, conjugated structure.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form biaryl and heterobiaryl systems.
• Chemical Biology & Proteomics: Employed as a versatile tag or linker in the design of chemical probes for studying protein function and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): A critical raw material for custom synthesis and scale-up projects requiring specialized fluorinated intermediates.

Basic Information

Product Name	2-Bromo-6-(3-(trifluoromethyl)phenyl)pyridine
CAS No.	180606-07-9
Molecular Formula	C12H7BrF3N
Molecular Weight	302.09 g/mol
Synonyms	2-Bromo-6-[3-(trifluoromethyl)phenyl]pyridine; 6-Bromo-2-(3-(trifluoromethyl)phenyl)pyridine; [3-(6-Bromopyridin-2-yl)phenyl]trifluoromethane; 2-(3-(Trifluoromethyl)phenyl)-6-bromopyridine; 180606-07-9; 2-Bromo-6-(alpha,alpha,α-trifluoro-m-tolyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(3-(trifluoromethyl)phenyl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.