Description

n-(5-Bromo-Pyridin-2-Yl)-2,4-Dioxo-4-Phenyl-Butyramide is a high-purity, synthetic organic compound featuring a brominated pyridine core, serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in enabling the precise construction of complex molecular architectures, particularly for pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes for studying enzyme function and biological pathways due to its modifiable bromo and amide functionalities.
• Material Science Precursor: Acts as a precursor for specialty polymers and organic electronic materials requiring specific nitrogen-containing heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	n-(5-Bromo-Pyridin-2-Yl)-2,4-Dioxo-4-Phenyl-Butyramide
CAS No.	180537-70-6
Molecular Formula	C15H11BrN2O3
Molecular Weight	347.17 g/mol
Synonyms	5-Bromo-N-(2,4-dioxo-4-phenylbutanoyl)pyridin-2-amine; 4-Phenyl-2,4-dioxo-N-(5-bromopyridin-2-yl)butanamide; 180537-70-6; 2,4-Dioxo-4-phenyl-N-(5-bromopyridin-2-yl)butyramide; Butyramide, N-(5-bromo-2-pyridinyl)-2,4-dioxo-4-phenyl-; N-(5-Bromo-2-pyridyl)-2,4-dioxo-4-phenylbutyramide
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-Pyridin-2-Yl)-2,4-Dioxo-4-Phenyl-Butyramide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.