Description

Spiro[Indene-1,4'-Piperidin]-3(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and neurological disorder therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis under GMP conditions.
• Academic & Institutional R&D: Employed in chemical biology and pharmacology research to explore new molecular entities.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	Spiro[Indene-1,4'-Piperidin]-3(2H)-One
CAS No.	180465-55-8
Molecular Formula	C13H15NO
Molecular Weight	201.27 g/mol
Synonyms	3H-Spiro[1-benzofuran-2,4'-piperidin]-3-one; 1,2-Dihydrospiro[indene-1,4'-piperidin]-3-one; Spiro[indene-1,4'-piperidine]-3(2H)-one; 180465-55-8; Spiro(indene-1,4'-piperidin)-3-one; Spiro[benzofuran-2,4'-piperidin]-3(3H)-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. We adhere to strict internal specifications to guarantee identity, purity, and consistency. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.