Description

Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester (9Ci) is a highly functionalized, strained bicyclic organic compound that serves as a valuable and versatile building block in advanced synthetic chemistry. Its unique three-dimensional, rigid scaffold and dual functional groups make it a critical intermediate for constructing complex molecular architectures with tailored properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, ligand design, and the development of novel polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bioactive molecules and active pharmaceutical ingredients (APIs), particularly those requiring rigid, three-dimensional cores to improve binding affinity and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its unique structure can impart new modes of action.
• Materials Science Research: Serves as a building block for advanced organic materials, including liquid crystals, metal-organic frameworks (MOFs), and polymers with specific mechanical or optical properties.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and tags due to its reactive aldehyde and ester functionalities, useful for bioconjugation and labeling studies.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, enabling novel ring-opening and cross-coupling reactions.

Basic Information

Product Name	Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester (9Ci)
CAS No.	180464-92-0
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	Methyl 3-formylbicyclo[1.1.1]pentane-1-carboxylate; 3-Formylbicyclo[1.1.1]pentane-1-carboxylic acid methyl ester; Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester; 1-(Methoxycarbonyl)bicyclo[1.1.1]pentane-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-formyl-, methyl ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Assay	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.