Description

3-(Boc-Amino)-4-Picoline is a protected amine derivative of 4-methylpyridine, serving as a crucial building block in organic synthesis. This compound matters because it provides a stable, orthogonal protecting group for primary amines, enabling selective reactions in complex multi-step syntheses. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of active pharmaceutical ingredients (APIs), fine chemicals, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to protect amino groups during chain elongation.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Precursor for synthesizing specialized ligands used in asymmetric catalysis and metal complexes.
• Chemical Biology Probes: Utilized in the creation of molecular probes and labeled compounds for biochemical research.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploratory organic synthesis in research laboratories.

Basic Information

Product Name	3-(Boc-Amino)-4-Picoline
CAS No.	180253-66-1
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	tert-Butyl (4-methylpyridin-3-yl)carbamate; 3-((tert-Butoxycarbonyl)amino)-4-methylpyridine; 4-Methyl-3-((tert-butoxycarbonyl)amino)pyridine; 3-(Boc-amino)-4-picoline; 3-(tert-Butoxycarbonylamino)-4-methylpyridine; Boc-3-amino-4-picoline; 3-Amino-4-picoline Boc derivative
EINECS	Contact for details

Quality Control

Our 3-(Boc-Amino)-4-Picoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.