Description

5-Methyl-4,5-Dihydro-3H,3'H-Spiro[Furan-2,1'-Isobenzofuran]-3'-One is a high-value, complex spirocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique fused furan-isobenzofuran structure makes it an essential intermediate for developing novel pharmaceuticals and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in developing new generation pesticides and herbicides with unique modes of action.
• Material Science: Building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis: Versatile spirocyclic scaffold for constructing complex natural product analogs and heterocyclic compounds in academic and industrial R&D.
• Chemical Biology: Probe or ligand in the development of biochemical tools and diagnostic agents.

Basic Information

Product Name	5-Methyl-4,5-Dihydro-3H,3'H-Spiro[Furan-2,1'-Isobenzofuran]-3'-One
CAS No.	180198-87-2
Molecular Formula	C13H12O3
Molecular Weight	216.23 g/mol
Synonyms	5-Methyl-4,5-dihydro-3H-spiro[2-benzofuran-1,2'-furan]-3-one; 3'H-Spiro[furan-2,1'-isobenzofuran]-3'-one, 5-methyl-4,5-dihydro-; 5-Methyl-4,5-dihydrospiro[benzofuran-1,2'-furan]-3-one; Spiro[isobenzofuran-1,2'-furan]-3'-one derivative; 180198-87-2; 5-Methyl-4,5-dihydro-3H-spiro[2-benzofuran-1,2'-furan]-3-one; 5-Methyldihydrospiro[benzofuran-1,2'-furan]-3-one
EINECS	Contact for details

Quality Control

Our production of 5-Methyl-4,5-Dihydro-3H,3'H-Spiro[Furan-2,1'-Isobenzofuran]-3'-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. All materials are characterized using advanced analytical techniques, including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.