Description

3,3-Dimethyl-3H-Spiro[Benzo[C]Furan-1,4'-Piperidine] Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Preclinical Development: Employed in the scale-up synthesis of compounds for pharmacological and toxicological evaluation.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	3,3-Dimethyl-3H-Spiro[Benzo[C]Furan-1,4'-Piperidine] Hydrochloride
CAS No.	180160-92-3
Molecular Formula	C15H20ClNO
Molecular Weight	265.78 g/mol
Synonyms	3,3-Dimethyl-3H-spiro[2-benzofuran-1,4'-piperidine] hydrochloride; 3H-Spiro[2-benzofuran-1,4'-piperidine], 3,3-dimethyl-, hydrochloride; 3,3-Dimethyl-1,4-dihydrospiro[2-benzofuran-1,4'-piperidine] hydrochloride; Spiro[benzo[c]furan-1,4'-piperidine], 3,3-dimethyl-, hydrochloride; 180160-92-3; 3,3-Dimethylspiro[benzo[c]furan-1(3H),4'-piperidine] hydrochloride
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-3H-Spiro[Benzo[C]Furan-1,4'-Piperidine] Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.