Description

6-Cr, 6G (6-Carboxyrhodamine 6G Hydrochloride) is a high-purity, water-soluble derivative of the classic rhodamine 6G fluorophore, featuring a carboxylic acid functional group for conjugation. This compound is essential for researchers and manufacturers requiring a bright, photostable orange-red fluorescent label with superior aqueous solubility and covalent coupling capabilities. It is primarily needed by the biotechnology, diagnostics, and pharmaceutical development sectors for advanced applications in fluorescence detection and labeling.

Application

• Fluorescent Labeling & Probes: Covalent conjugation to biomolecules (antibodies, proteins, peptides, oligonucleotides) via its carboxylic acid group for use in fluorescence microscopy, flow cytometry, and in situ hybridization (FISH).
• Diagnostic Assay Development: Key component in the synthesis of fluorescent tracers and detection reagents for immunoassays (e.g., ELISA, lateral flow tests) and nucleic acid testing.
• Biomedical Research: Used as a cell-permeant dye for organelle staining and as a building block for developing novel sensor molecules and activity-based probes.
• Material Science & Nanotechnology: Functionalization of nanoparticles, polymers, and surfaces to impart fluorescence for tracking, imaging, and sensing applications.

Basic Information

Item	Detail
Product Name	6-Cr, 6G (6-Carboxyrhodamine 6G Hydrochloride)
CAS No.	180144-68-7
Molecular Formula	C29H29N2O3 · HCl
Molecular Weight	505.02 g/mol (Free base: 465.56)
Synonyms	6-Carboxyrhodamine 6G; 6-CR 6G; 6-Carboxy-X-rhodamine; 6-ROX; 5(6)-Carboxyrhodamine 6G hydrochloride; Rhodamine 6G carboxylic acid; C6R6G; 6-Carboxy-2',4,5,7-tetrabromorhodamine 6G (common mis-association corrected)
EINECS	Contact for details

Quality Control

Our 6-Carboxyrhodamine 6G Hydrochloride is manufactured under strict quality management systems. Each batch is characterized and tested to ensure high purity and consistent performance for sensitive applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and functional suitability is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	Dark red to purple powder
Identification (HPLC/UV-Vis)	Conforms to reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Absorption (λmax)	525 - 535 nm
Emission (λmax)	550 - 560 nm
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.