Description

4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1-Piperidineacetic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine-acetic acid ester structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially protease inhibitors and other neurologically active compounds.
• API Synthesis: Serves as a key chiral building block for constructing the core scaffold of target APIs, ensuring high stereochemical purity.
• Medicinal Chemistry Research: Used in research and development for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Employed in contract manufacturing organizations (CMOs) for the production of bespoke compounds and non-commercial research quantities.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1-Piperidineacetic Acid Methyl Ester
CAS No.	179688-99-4
Molecular Formula	C14H26N2O5
Molecular Weight	302.37 g/mol
Synonyms	1-Piperidineacetic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; Methyl 4-[(tert-butoxycarbonyl)amino]piperidine-1-acetate; 4-(Boc-amino)-1-piperidineacetic acid methyl ester; Boc-4-amino-piperidine-1-acetic acid methyl ester; 4-(N-Boc-amino)piperidine-1-acetic acid methyl ester; 1-Carboxymethyl-4-(N-Boc-amino)piperidine methyl ester; N-Boc-4-aminopiperidine-1-acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1-Piperidineacetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.