Description

6-Amino-4-Methyl-Nicotinic Acid Methyl Ester is a high-purity, versatile pyridine derivative and a key synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and specialized agrochemicals. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable building blocks for heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides where the pyridine core provides essential bioactivity.
• Fine Chemical Production: Serves as a precursor for various specialty chemicals, dyes, and functional materials requiring a substituted nicotinate scaffold.
• Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical entities.
• Ligand and Catalyst Preparation: Useful for synthesizing complex ligands for metal catalysis or as a component in organocatalysts.

Basic Information

Product Name	6-Amino-4-Methyl-Nicotinic Acid Methyl Ester
CAS No.	179555-12-5
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	Methyl 6-Amino-4-methylnicotinate; 6-Amino-4-methylpyridine-3-carboxylic acid methyl ester; 4-Methyl-6-aminonicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 6-amino-4-methyl-, methyl ester; Methyl 6-amino-4-methyl-3-pyridinecarboxylate; 6-Amino-4-methyl-3-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 6-Amino-4-Methyl-Nicotinic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and other relevant regulatory frameworks for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.