Description

5-Isopropylpyridine-2-Sulfonamide is a specialized heterocyclic sulfonamide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the sulfonamide moiety and pyridine core offer valuable pharmacophoric properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to create novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where a sulfonamide pharmacophore is beneficial.
• Agrochemical Synthesis: Used in the research and production of new-generation herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: The pyridine nitrogen and sulfonamide group make it a useful scaffold for designing chelating ligands in coordination chemistry and catalysis.
• Material Science Research: Employed as a monomer or functional additive in the development of advanced polymers with specific thermal or chemical properties.
• Chemical Biology Probe: Acts as a building block for creating molecular probes to study biological pathways and protein function.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Isopropylpyridine-2-Sulfonamide
CAS No.	179400-18-1
Molecular Formula	C9H14N2O2S
Molecular Weight	214.29 g/mol
Synonyms	2-Pyridinesulfonamide, 5-(1-methylethyl)-; 5-Isopropyl-2-pyridinesulfonamide; 5-(Propan-2-yl)pyridine-2-sulfonamide; 5-Isopropylpyridine-2-sulfonic acid amide; 5-(1-Methylethyl)-2-pyridinesulfonamide; 2-Sulfamoyl-5-isopropylpyridine
EINECS	Contact for details

Quality Control

Our 5-Isopropylpyridine-2-Sulfonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.