Description

Methyl 4-Bromo-2-Fluorobenzoate is a high-purity fluorinated aromatic ester building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogen substitution pattern enables precise molecular modifications. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the fluorine and bromine substituents for enhanced bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic cores used in electronic display technologies.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Material Research: Employed in academic and industrial R&D for developing novel polymers and ligands with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	Methyl 4-Bromo-2-Fluorobenzoate
CAS No.	179232-29-2
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	4-Bromo-2-fluorobenzoic acid methyl ester; Methyl 4-bromo-2-fluorobenzoate; 2-Fluoro-4-bromobenzoic acid methyl ester; Benzoic acid, 4-bromo-2-fluoro-, methyl ester; Methyl 2-fluoro-4-bromobenzoate; 4-Bromo-2-fluorobenzoic acid, methyl ester; Methyl ester of 4-bromo-2-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-2-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.