Description

tert-Butyl 2-(5-Bromopyridin-3-yl)piperidine-1-carboxylate is a high-value, protected piperidine derivative featuring a brominated pyridine moiety. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in modern organic synthesis. It is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to construct complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used as a building block for developing novel crop protection agents and herbicides.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Ligand & Catalyst Development: The bromopyridine group allows for further functionalization via cross-coupling reactions, making it useful for creating novel ligands and catalysts.
• Material Science: Potential monomer or precursor for specialty polymers and functional materials.

Basic Information

Product Name	tert-Butyl 2-(5-Bromopyridin-3-yl)piperidine-1-carboxylate
CAS No.	179119-98-3
Molecular Formula	C15H21BrN2O2
Molecular Weight	341.25 g/mol
Synonyms	1-Boc-2-(5-bromo-3-pyridyl)piperidine; 1-(tert-Butoxycarbonyl)-2-(5-bromopyridin-3-yl)piperidine; tert-Butyl 2-(5-bromo-3-pyridinyl)-1-piperidinecarboxylate; 2-(5-Bromopyridin-3-yl)piperidine-1-carboxylic acid tert-butyl ester; 5-Bromo-3-(1-Boc-piperidin-2-yl)pyridine; 179119-98-3; Boc-2-(5-bromo-3-pyridyl)piperidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 2-(5-Bromopyridin-3-yl)piperidine-1-carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.