Description

tert-Butyl 2-Bromo-2-(Diethoxyphosphoryl)Acetate is a high-value organophosphorus building block essential for advanced synthetic chemistry. This compound matters for its unique reactivity profile, enabling the efficient construction of complex molecules through Horner-Wadsworth-Emmons (HWE) and related olefination reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of α,β-unsaturated esters and other olefin-containing bioactive molecules.
• Agrochemical Synthesis: Used to construct complex alkenes and heterocyclic frameworks found in modern pesticides and herbicides.
• Material Science Research: Employed in the development of novel polymers and functional materials requiring precise olefin installation.
• Academic & R&D Laboratories: A versatile reagent for methodological development in organic synthesis and catalysis studies.
• Peptidomimetics & Prodrug Synthesis: Useful for introducing ester-protected, phosphoryl-activated moieties into complex molecular architectures.

Basic Information

Product Name	tert-Butyl 2-Bromo-2-(Diethoxyphosphoryl)Acetate
CAS No.	179106-93-5
Molecular Formula	C₁₀H₂₀BrO₅P
Molecular Weight	331.14 g/mol
Synonyms	Diethyl (2-Bromo-2-tert-butoxy-2-oxoethyl)phosphonate; 2-Bromo-2-(diethoxyphosphoryl)acetic acid tert-butyl ester; tert-Butyl bromo(diethoxyphosphoryl)acetate; (2-Bromo-2-tert-butoxy-2-oxoethyl)phosphonic acid diethyl ester; Bromo(diethoxyphosphoryl)acetic Acid tert-Butyl Ester; Acetic acid, 2-bromo-2-(diethoxyphosphinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromo-2-(Diethoxyphosphoryl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Handle and store under an inert atmosphere for optimal long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.