Description

Methyl 5-(Chloromethyl)Nicotinate Hydrochloride is a high-purity, advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for building sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly for neurological and metabolic disorder treatments.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides.
• Chemical Research: Serves as a versatile precursor in organic synthesis for creating novel heterocyclic compounds.
• API Development: Integral in the production chain for Active Pharmaceutical Ingredients requiring nicotinate-based structures.
• Bioconjugation Chemistry: The chloromethyl group enables its use in linker chemistry for antibody-drug conjugates (ADCs) and other targeted therapies.

Basic Information

Product Name	Methyl 5-(Chloromethyl)Nicotinate Hydrochloride
CAS No.	179072-14-1
Molecular Formula	C8H9Cl2NO2
Molecular Weight	222.07 g/mol
Synonyms	5-(Chloromethyl)nicotinic acid methyl ester hydrochloride; Methyl 5-(chloromethyl)pyridine-3-carboxylate hydrochloride; 3-Pyridinecarboxylic acid, 5-(chloromethyl)-, methyl ester, hydrochloride; Nicotinic acid, 5-(chloromethyl)-, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 5-(Chloromethyl)Nicotinate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.