Description

tert-Butyl 6,7-Dihydrofuro[3,2-C]Pyridine-5(4H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its fused furopyridine structure. This compound is of significant value for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Process Chemistry Development: Used in the optimization and scale-up of synthetic routes for candidate drugs during preclinical and clinical development phases.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of drug substances for clinical trials.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	tert-Butyl 6,7-Dihydrofuro[3,2-C]Pyridine-5(4H)-Carboxylate
CAS No.	179060-34-5
Molecular Formula	C12H15NO3
Molecular Weight	221.25 g/mol
Synonyms	4,5,6,7-Tetrahydrofuro[3,2-c]pyridine-5-carboxylic acid tert-butyl ester; tert-Butyl 4,5,6,7-tetrahydrofuro[3,2-c]pyridine-5-carboxylate; 5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrofuro[3,2-c]pyridine; 6,7-Dihydro-4H-furo[3,2-c]pyridine-5-carboxylic acid, 1,1-dimethylethyl ester; BOC-protected tetrahydrofuropyridine; Furo[3,2-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 6,7-Dihydrofuro[3,2-C]Pyridine-5(4H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.