Description

4-(tert-Butyldimethylsilyloxy)Methylbenzhydrazide is a high-purity, protected benzhydrazide derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which offers exceptional stability under a wide range of reaction conditions, enabling precise multi-step synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those requiring protected hydrazide functionalities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Conjugate Chemistry: Facilitates the creation of hydrazide-linked bioconjugates and peptide analogs for therapeutic and diagnostic applications.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and advanced organic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Item	Detail
Product Name	4-(tert-Butyldimethylsilyloxy)Methylbenzhydrazide
CAS No.	179055-96-0
Molecular Formula	C14H24N2O2Si
Molecular Weight	280.44 g/mol
Synonyms	4-[(tert-Butyldimethylsilyloxy)methyl]benzhydrazide; 4-(Hydroxymethyl)benzhydrazide TBDMS ether; N'-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]benzoyl]hydrazine; TBDMS-protected 4-Hydroxymethylbenzhydrazide; 4-(TBDMS-oxymethyl)benzohydrazide; Benzhydrazide, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyldimethylsilyloxy)Methylbenzhydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.