Description

3-tert-Butoxycarbonylamino-Isonicotinic Acid is a high-purity, protected amino acid derivative and a key pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a reactive carboxylic acid group and a Boc-protected amine for selective deprotection and further functionalization. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Peptide Synthesis: Serves as a protected amino acid component in solid-phase and solution-phase peptide synthesis for research and development.
• Agrochemical Research: Used in the development and production of advanced crop protection agents and other specialty agrochemicals.
• Chemical Biology Probes: Employed in the creation of labeled compounds and molecular probes for biochemical and cellular research applications.
• Custom Synthesis & Contract Manufacturing: A starting material for custom chemical synthesis services catering to the needs of biotechnology and pharmaceutical companies.
• Academic & Industrial R&D: A valuable reagent for organic synthesis research in academic laboratories and industrial R&D departments.

Basic Information

Item	Details
Product Name	3-tert-Butoxycarbonylamino-Isonicotinic Acid
CAS No.	179024-65-8
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]isonicotinic acid; 3-(Boc-amino)isonicotinic acid; 3-(tert-Butoxycarbonylamino)pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-; Boc-3-amino-4-pyridinecarboxylic acid; 3-Boc-amino-4-pyridinecarboxylic acid; 3-(N-Boc-amino)isonicotinic acid; 179024-65-8
EINECS	Contact for details

Quality Control

Our 3-tert-Butoxycarbonylamino-Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.