Description

Methyl 6-Amino-5-Bromopicolinate is a high-purity, versatile brominated picolinate ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering both a bromo substituent for cross-coupling reactions and an amino group for further derivatization, enabling the construction of complex heterocyclic scaffolds. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate for creating functionalized polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: The bromo group is amenable to Suzuki, Stille, and Buchwald-Hartwig amination reactions for carbon-carbon and carbon-nitrogen bond formation.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in academic and industrial R&D laboratories.

Basic Information

Product Name	Methyl 6-Amino-5-Bromopicolinate
CAS No.	178876-82-9
Molecular Formula	C7H7BrN2O2
Molecular Weight	231.05 g/mol
Synonyms	5-Bromo-6-aminopicolinic acid methyl ester; Methyl 5-bromo-6-aminopyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 6-amino-5-bromo-, methyl ester; 6-Amino-5-bromo-2-pyridinecarboxylic acid methyl ester; 5-Bromo-2-methoxycarbonylpyridin-6-amine; Methyl 6-amino-5-bromopyridine-2-carboxylate; 178876-82-9
EINECS	Contact for details

Quality Control

Our Methyl 6-Amino-5-Bromopicolinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.