Description

3-tert-Butylthio-2-Carboxypyridine is a specialized heterocyclic building block featuring both a carboxylic acid and a tert-butylthioether functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for modifying pharmacokinetic properties.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the pyridine core and sulfur moiety are common pharmacophores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing probes that study enzyme function or biological pathways due to its reactive handles.

Basic Information

Product Name	3-tert-Butylthio-2-Carboxypyridine
CAS No.	178811-41-1
Molecular Formula	C11H15NO2S
Molecular Weight	225.31 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-[(1,1-dimethylethyl)thio]-; 3-(tert-Butylthio)picolinic acid; 3-(tert-Butylsulfanyl)pyridine-2-carboxylic acid; 3-(tert-Butylmercapto)-2-pyridinecarboxylic acid; 3-tert-Butylsulfanylpyridine-2-carboxylic acid; 3-(tert-Butylthio)picolinate; 3-(tert-C4H9S)-2-C5H3NCOOH
EINECS	Contact for details

Quality Control

Our 3-tert-Butylthio-2-Carboxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.