Description

Cyclopropanol, 2-Ethoxy-1-Ethynyl-, Methanesulfonate, (1S-Trans)- (9Ci) is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclopropanol ring, ethynyl group, and methanesulfonate leaving group, makes it a valuable precursor for constructing complex, stereodefined molecular architectures. This high-purity intermediate is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Methodology Development: Serves as a substrate in academic and industrial research for developing new catalytic and stereoselective synthetic transformations.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing sophisticated chiral ligands and organometallic catalysts.
• Material Science Research: Potential building block for advanced organic materials and polymers requiring specific geometric constraints.

Basic Information

Product Name	Cyclopropanol, 2-Ethoxy-1-Ethynyl-, Methanesulfonate, (1S-Trans)- (9Ci)
CAS No.	178751-91-2
Molecular Formula	C8H12O4S
Molecular Weight	204.24 g/mol
Synonyms	(1S-trans)-2-Ethoxy-1-ethynylcyclopropyl methanesulfonate; (1S,2S)-2-Ethoxy-1-ethynylcyclopropyl methanesulfonate; trans-2-Ethoxy-1-ethynylcyclopropyl methanesulfonate; (1S-trans)-Cyclopropanol, 2-ethoxy-1-ethynyl-, methanesulfonate; 178751-91-2; (1S,2S)-2-Ethoxy-1-ethynylcyclopropyl mesylate
EINECS	Contact for details

Quality Control

Our production of Cyclopropanol, 2-Ethoxy-1-Ethynyl-, Methanesulfonate, (1S-Trans)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity assessment by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.