Description

Silane, [(2-Ethoxy-1-Methoxycyclopropyl)Ethynyl]Trimethyl-, (1S-Trans)- (9Ci) is a specialized organosilicon compound featuring a unique functionalized cyclopropyl and ethynyl group attached to a trimethylsilane core. This molecule matters as a high-value, stereochemically defined building block for advanced organic synthesis, particularly in the development of novel pharmaceuticals and complex natural products. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce silicon-containing motifs or rigid, three-dimensional scaffolds into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for introducing silicon isosteres or constrained ring systems.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the silane and cyclopropyl groups can impart specific biological activity and stability.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and silicon-based hybrid materials with tailored properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cycloadditions, and other transformative organic reactions to construct complex molecular architectures.
• Ligand and Catalyst Development: Utilized for the preparation of novel chiral ligands or organometallic catalysts for asymmetric synthesis.
• Chemical Research (R&D): A valuable tool for academic and industrial research groups exploring new synthetic methodologies and reaction pathways involving organosilicon chemistry.

Basic Information

Product Name	Silane, [(2-Ethoxy-1-Methoxycyclopropyl)Ethynyl]Trimethyl-, (1S-Trans)- (9Ci)
CAS No.	178751-90-1
Molecular Formula	C13H24O2Si
Molecular Weight	240.42 g/mol
Synonyms	[(2-Ethoxy-1-methoxycyclopropyl)ethynyl]trimethylsilane; (1S-trans)-[(2-Ethoxy-1-methoxycyclopropyl)ethynyl]trimethylsilane; Trimethyl[(2-ethoxy-1-methoxycyclopropyl)ethynyl]silane; (1S,2R)-1-Ethoxy-2-methoxy-2-[(trimethylsilyl)ethynyl]cyclopropane; A functionalized cyclopropylacetylene silane; (1S-trans)-Form
EINECS	Contact for details

Quality Control

Our high-purity Silane, [(2-Ethoxy-1-Methoxycyclopropyl)Ethynyl]Trimethyl-, (1S-Trans)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure consistent identity, strength, and stereochemical integrity. Certificates of Analysis (COA) detailing specifications such as assay (by GC/HPLC), enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.