Description

Spiro[1-Azabicyclo[2.2.2]Octane-3,5-Oxazolidin]-2-One, (3S)- (9Ci) is a sophisticated spirocyclic organic compound featuring a bridged bicyclic structure fused with an oxazolidinone ring. This molecule is of significant interest as a key chiral building block and advanced intermediate in modern pharmaceutical synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates.
• Neurological Drug Research: Used in the synthesis of compounds targeting nicotinic acetylcholine receptors for potential treatments of cognitive disorders.
• Medicinal Chemistry: Acts as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective chemical transformations.
• Process Chemistry Development: Used for scaling up synthetic routes in pilot plants and commercial manufacturing.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development services.

Basic Information

Product Name	Spiro[1-Azabicyclo[2.2.2]Octane-3,5-Oxazolidin]-2-One, (3S)- (9Ci)
CAS No.	178419-47-1
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(3S)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin]-2'-one; (3S)-Spiro[1-azabicyclo[2.2.2]octane-3,5-oxazolidin]-2-one; (3S)-Spiro[quinuclidine-3,5'-oxazolidin]-2'-one; (S)-Spiro[quinuclidine-3,5'-oxazolidin]-2'-one; 178419-47-1; Spiro[1-Azabicyclo[2.2.2]Octane-3,5-Oxazolidin]-2-One, (3S)-; Spiro[quinuclidine-3,5'-oxazolidin]-2'-one, (3S)-
EINECS	Contact for details

Quality Control

Our Spiro[1-Azabicyclo[2.2.2]Octane-3,5-Oxazolidin]-2-One, (3S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.