Description

Spiro[1-Azabicyclo[2.2.2]Octane-3,5-Oxazolidin]-2-One (9Ci) is a complex spirocyclic organic compound featuring a fused oxazolidinone and quinuclidine-like structure, making it a valuable and sophisticated synthetic intermediate. Its unique three-dimensional architecture is crucial for constructing molecules with specific biological activity and stereochemical complexity. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis projects.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its rigid spirocyclic core can contribute to unique modes of action and improved environmental profiles.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Chemical Biology Probe Synthesis: Employed in the construction of molecular probes for studying enzyme mechanisms and protein-ligand interactions within biological systems.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specialized thermal or mechanical properties due to its constrained geometry.

Basic Information

Product Name	Spiro[1-Azabicyclo[2.2.2]Octane-3,5-Oxazolidin]-2-One (9Ci)
CAS No.	178419-45-9
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin]-2'-one; 1-Azaspiro[bicyclo[2.2.2]octane-3,5'-oxazolidin]-2'-one; 178419-45-9; Spiro(quinuclidine-3,5'-oxazolidin)-2'-one; 1-Azabicyclo[2.2.2]octane, spiro compound with oxazolidin-2-one; (9CI) Spiro compound
EINECS	Contact for details

Quality Control

Our Spiro[1-Azabicyclo[2.2.2]Octane-3,5-Oxazolidin]-2-One (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.