Description

Ethyl 2-(5-Oxo-3-(Pyridin-2-Yl)Pyrrolidin-3-Yl)Acetate is a high-value, advanced pharmaceutical intermediate featuring a complex pyrrolidinone scaffold fused with a pyridine moiety. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) and inflammatory pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of proprietary drug candidates, particularly in neurological and anti-inflammatory research.
• Organic Synthesis Research: Serves as a versatile precursor for constructing complex heterocyclic compounds in medicinal chemistry.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for scale-up and GMP production.
• Academic & R&D: Used in university and corporate R&D labs for exploratory synthesis and structure-activity relationship (SAR) studies.
• Reference Standard: Sourced for analytical method development and quality control as a high-purity reference material.

Basic Information

Product Name	Ethyl 2-(5-Oxo-3-(Pyridin-2-Yl)Pyrrolidin-3-Yl)Acetate
CAS No.	178372-18-4
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	Ethyl (5-oxo-3-(pyridin-2-yl)pyrrolidin-3-yl)acetate; 2-(5-Oxo-3-(2-pyridinyl)-3-pyrrolidinyl)acetic Acid Ethyl Ester; 3-Pyridin-2-yl-3-pyrrolidin-5-one-3-acetic Acid Ethyl Ester; 178372-18-4; Ethyl 2-(5-oxo-3-pyridin-2-ylpyrrolidin-3-yl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5-Oxo-3-(Pyridin-2-Yl)Pyrrolidin-3-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.