Description

Ethyl 4,4-Difluorocyclohexanecarboxylate is a high-purity fluorinated building block essential for advanced organic synthesis. This compound is valued for its unique cyclohexane ring structure and strategically placed fluorine atoms, which are critical for modulating the physicochemical properties of target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing lipophilicity and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluorocyclohexyl moiety can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for specialty polymers and liquid crystals that require fluorinated components for specific performance characteristics.
• Organic Synthesis Reagent: Employed in various carbon-carbon bond formation reactions, such as alkylations and cross-couplings, to construct complex molecular architectures.
• Fluorine Chemistry Research: An important compound for academic and industrial research exploring the effects of fluorine substitution on chemical reactivity and molecular conformation.

Basic Information

Product Name	Ethyl 4,4-Difluorocyclohexanecarboxylate
CAS No.	178312-47-5
Molecular Formula	C9H14F2O2
Molecular Weight	192.20 g/mol
Synonyms	4,4-Difluorocyclohexanecarboxylic Acid Ethyl Ester; Ethyl 4,4-Difluorocyclohexanecarboxylate; 4,4-Difluorocyclohexanecarboxylic Acid Ethyl Ester; Ethyl 4,4-Difluorocyclohexane-1-carboxylate; Cyclohexanecarboxylic acid, 4,4-difluoro-, ethyl ester; 1-Carbethoxy-4,4-difluorocyclohexane
EINECS	Contact for details

Quality Control

Our Ethyl 4,4-Difluorocyclohexanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.