Description

Ethyl 6-(Bromomethyl)Pyridine-3-Carboxylate is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive bromomethyl group and ester functionality, enabling precise molecular construction. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its modifiable aromatic system.
• Cross-Coupling Reactions: The bromomethyl group acts as an effective handle for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Bioconjugation and Probe Synthesis: Useful for attaching reporter molecules or affinity tags in the development of biochemical probes and diagnostic agents.

Basic Information

Item	Details
Product Name	Ethyl 6-(Bromomethyl)Pyridine-3-Carboxylate
CAS No.	178264-57-8
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	Ethyl 6-(Bromomethyl)Nicotinate; 3-Pyridinecarboxylic acid, 6-(bromomethyl)-, ethyl ester; 6-(Bromomethyl)nicotinic acid ethyl ester; Ethyl 6-bromomethylnicotinate; 5-(Ethoxycarbonyl)-2-(bromomethyl)pyridine; 2-(Bromomethyl)-5-ethoxycarbonylpyridine; Ethyl 5-(bromomethyl)pyridine-3-carboxylate (regioisomer reference)
EINECS	Contact for details

Quality Control

Every batch of Ethyl 6-(Bromomethyl)Pyridine-3-Carboxylate is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for research and process chemistry. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to guarantee identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.