Description

7-Azabicyclo[2.2.1]Heptane-2-Carboxylicacid,Methylester,(1R,2R,4S)-Rel- is a high-purity, stereochemically defined bicyclic amino acid ester derivative that serves as a critical chiral building block in advanced organic synthesis. Its rigid, constrained scaffold is essential for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, including protease inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in antiviral and neurological disorder research.
• Protease Inhibitor Scaffold: Used in the design and development of novel inhibitors targeting specific enzymes.
• Agrochemical Synthesis: Employed as a building block for creating enantiomerically pure active ingredients with specific biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Peptidomimetics Research: Integral for constructing conformationally restricted peptide analogs to enhance stability and bioavailability.
• Academic & Contract Research: Utilized in academic laboratories and CROs for methodological development and exploring new chemical space.

Basic Information

Item	Details
Product Name	7-Azabicyclo[2.2.1]Heptane-2-Carboxylicacid,Methylester,(1R,2R,4S)-Rel-
CAS No.	178241-05-9
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	(1R,2R,4S)-Methyl 7-azabicyclo[2.2.1]heptane-2-carboxylate; rel-(1R,2R,4S)-Methyl 7-azabicyclo[2.2.1]heptane-2-carboxylate; Methyl (1R,2R,4S)-7-azabicyclo[2.2.1]heptane-2-carboxylate; 7-Azanorbornane-2-carboxylic acid methyl ester; Bicyclic proline derivative; 2-Carbomethoxy-7-azabicyclo[2.2.1]heptane
EINECS	Contact for details

Quality Control

Every batch of 7-Azabicyclo[2.2.1]Heptane-2-Carboxylicacid,Methylester,(1R,2R,4S)-Rel- is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to ensure identity, purity, and enantiomeric excess meet rigorous standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.