Description

2-Methylsulfonyl-5-Trifluoromethylpyridine is a high-purity, multi-functional heterocyclic building block of significant commercial interest. Its unique structure, featuring both a sulfonyl and a trifluoromethyl group on a pyridine ring, makes it a critical intermediate for the synthesis of advanced active ingredients. This compound is primarily sought after by research and development teams in the agrochemical and pharmaceutical sectors for creating novel compounds with enhanced biological activity and physicochemical properties.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern pesticides, including herbicides and insecticides, where the trifluoromethyl and sulfonyl groups contribute to improved efficacy and environmental profile.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Material Science Research: Serves as a building block for developing novel functional materials, such as liquid crystals, organic semiconductors, and advanced polymers.
• Cross-Coupling Reactions: The pyridine core and functional groups make it a valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex molecular architectures.
• Chemical Synthesis Reagent: Employed in organic synthesis laboratories as a versatile reagent for introducing specific functional groups into target molecules.

Basic Information

Product Name	2-Methylsulfonyl-5-Trifluoromethylpyridine
CAS No.	178204-50-7
Molecular Formula	C7H6F3NO2S
Molecular Weight	225.19 g/mol
Synonyms	5-(Trifluoromethyl)-2-(methylsulfonyl)pyridine; 2-(Methylsulfonyl)-5-(trifluoromethyl)pyridine; 5-Trifluoromethyl-2-methylsulfonylpyridine; 2-Methanesulfonyl-5-trifluoromethylpyridine; 2-Mesyl-5-trifluoromethylpyridine; Pyridine, 2-(methylsulfonyl)-5-(trifluoromethyl)-; 178204-50-7
EINECS	Contact for details

Quality Control

Our 2-Methylsulfonyl-5-Trifluoromethylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.