Description

4-Nitrophenyl 2-Fluoropropionate is a specialized fluorinated ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a fluorinated moiety and a reactive phenolic ester group, making it a versatile intermediate for introducing specific functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and complex molecules requiring precise fluorination.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and prodrugs.
• Agrochemical Research: Used in developing novel herbicides, pesticides, and fungicides with enhanced properties through fluorination.
• Chemical Biology & Proteomics: Acts as an active ester for labeling and modifying biomolecules, peptides, and proteins.
• Material Science: Building block for creating specialty polymers and liquid crystals with tailored electronic and optical characteristics.
• Organic Synthesis: Versatile reagent for esterification and acylation reactions under mild conditions.
• Fluorine Chemistry Research: Fundamental compound for studying the effects of fluorine substitution on chemical reactivity and biological activity.

Basic Information

Product Name	4-Nitrophenyl 2-Fluoropropionate
CAS No.	178181-33-4
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	2-Fluoropropionic Acid 4-Nitrophenyl Ester; p-Nitrophenyl 2-Fluoropropionate; 4-Nitrophenyl α-Fluoropropionate; 2-Fluoro-1-(4-nitrophenoxy)-1-oxopropane; 4-Nitrophenyl 2-fluoropropanoate; 2-Fluoropropanoic Acid 4-Nitrophenyl Ester; PNFP
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl 2-Fluoropropionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with every shipment, documenting identity, purity, and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its ester nature and light-sensitive properties, prolonged exposure to light or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.