Description

Cyclopropanecarboxylic Acid, 2-Acetyl-, Methyl Ester, (1R-Cis)- (9Ci) is a high-purity, chiral cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries where precise stereochemistry is required. The product, identified by CAS number 178033-26-6, is supplied to meet the stringent demands of modern chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those requiring the cis-substituted cyclopropane motif for biological activity.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the cyclopropane ring can confer specific stability and activity profiles.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Acetyl-, Methyl Ester, (1R-Cis)- (9Ci)
CAS No.	178033-26-6
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	(1R,2S)-2-Acetylcyclopropanecarboxylic acid methyl ester; Methyl (1R,2S)-2-acetylcyclopropanecarboxylate; (1R-cis)-2-Acetylcyclopropanecarboxylic Acid Methyl Ester; trans-(1R,2S)-2-Acetylcyclopropanecarboxylic Acid Methyl Ester; (1R,2S)-Methyl 2-acetylcyclopropanecarboxylate; (1R,2S)-2-Acetyl-1-cyclopropanecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Acetyl-, Methyl Ester, (1R-Cis)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Production adheres to cGMP guidelines where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.