Description

tert-Butyl 4-Ethynyl-5,6-dihydropyridine-1(2H)-carboxylate is a versatile and high-value protected piperidine derivative featuring a reactive ethynyl group. This compound is a critical pharmaceutical intermediate and advanced building block for organic synthesis, enabling the construction of complex nitrogen-containing heterocycles. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and other therapeutic areas.
• Organic Synthesis Building Block: Used in click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition) and cross-coupling reactions to introduce the ethynyl functionality into larger molecular frameworks.
• Agrochemical Research: Serves as a starting material for developing novel pesticides and herbicides with specific biological activity.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Used in the research and development of specialty polymers and advanced organic materials with tailored properties.

Basic Information

Product Name	tert-Butyl 4-Ethynyl-5,6-dihydropyridine-1(2H)-carboxylate
CAS No.	177984-28-0
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	1-Boc-4-ethynyl-1,2,3,6-tetrahydropyridine; 4-Ethynyl-1,2,3,6-tetrahydropyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-ethynyl-3,6-dihydro-2H-pyridine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-ethynyl-1,2,3,6-tetrahydropyridine; 4-Ethynyl-N-Boc-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydro-4-ethynylpyridine-1-carboxylic acid tert-butyl ester; Boc-4-ethynyl-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Ethynyl-5,6-dihydropyridine-1(2H)-carboxylate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.