Description

3-(Chloromethyl)-5-(4-Fluorophenyl)Pyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive chloromethyl group and a fluorinated aromatic ring, makes it an essential intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl-pyridine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or components for OLEDs.
• Custom Chemical Synthesis: A valuable scaffold for contract research organizations (CROs) and CDMOs producing custom fine chemicals for client projects.
• Academic & Industrial R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	3-(Chloromethyl)-5-(4-Fluorophenyl)Pyridine
CAS No.	177976-33-9
Molecular Formula	C12H9ClFN
Molecular Weight	221.66 g/mol
Synonyms	5-(4-Fluorophenyl)-3-(chloromethyl)pyridine; 3-Chloromethyl-5-(4-fluorophenyl)pyridine; (4-Fluorophenyl)-5-(3-pyridinyl)methyl chloride; 177976-33-9; 5-(4-Fluorophenyl)-3-pyridinechloromethane; 3-Pyridinechloromethane, 5-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-5-(4-Fluorophenyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.