Description

Alanine, 2-Methyl-, Phenyl Ester is a specialized amino acid derivative ester, identified by CAS NO 177960-04-2, valued for its role as a key chiral building block and intermediate in advanced organic synthesis. This compound is particularly significant for introducing the 2-methylalanine (α-aminoisobutyric acid) moiety into target molecules, a structural feature known to influence peptide conformation and stability. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active compounds and materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Peptidomimetics Research: Serves as a building block for constructing peptidomimetics and conformationally constrained peptides in medicinal chemistry.
• Fine Chemical Production: Employed in multi-step synthetic routes for producing complex, high-value specialty chemicals and flavors/fragrances.
• Academic & R&D Laboratories: Utilized in fundamental research exploring new synthetic methodologies and structure-activity relationships.
• Material Science: Potential intermediate for synthesizing specialized polymers or coatings with tailored properties.

Basic Information

Product Name	Alanine, 2-Methyl-, Phenyl Ester
CAS No.	177960-04-2
Molecular Formula	C₁₁H₁₅NO₂
Molecular Weight	193.24 g/mol
Synonyms	2-Methylalanine phenyl ester; Phenyl 2-aminoisobutyrate; α-Aminoisobutyric acid phenyl ester; (RS)-2-Amino-2-methylpropanoic acid phenyl ester; 2-Amino-2-methyl-propionic acid phenyl ester; Aib-OPh; DL-2-Aminoisobutyric acid phenyl ester
EINECS	Contact for details

Quality Control

Our Alanine, 2-Methyl-, Phenyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for synthetic applications. We provide detailed Certificates of Analysis (COA) with key parameters such as assay (by HPLC or titration), enantiomeric excess, and impurity profiles. Our quality system is designed to support cGMP and ISO-guided processes for reliable and consistent supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This material may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.