Description

3-Methoxybenzylisocyanide is a versatile and high-value organic building block, specifically an isocyanide derivative of 3-methoxybenzylamine. This compound is essential for facilitating the synthesis of complex heterocyclic and peptidomimetic structures through multicomponent reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for lead optimization and novel compound library generation.

Application

• Pharmaceutical Intermediate: A key reagent in the Ugi, Passerini, and other multicomponent reactions for the rapid assembly of diverse chemical libraries for drug discovery.
• Agrochemical Synthesis: Employed in the construction of novel fungicides, herbicides, and insecticides with complex molecular architectures.
• Material Science Research: Used as a precursor for the development of functional polymers, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Facilitates the synthesis of activity-based probes and bioconjugates for studying biological pathways.
• Academic & Industrial R&D: Serves as a fundamental building block in methodological development and synthetic organic chemistry research.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	3-Methoxybenzylisocyanide
CAS No.	177762-74-2
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	1-Isocyano-3-methoxybenzene; (3-Methoxyphenyl)methyl isocyanide; 3-Methoxybenzyl isonitrile; m-Methoxybenzyl isocyanide; 3-Methoxybenzyl Isocyanide; 3-Methoxybenzylisonitrile; (3-Methoxyphenyl)methaneisonitrile; 3-Methoxybenzyl Isonitrile
EINECS	Contact for details

Quality Control

Our 3-Methoxybenzylisocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards. For specialized applications, custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.