Description

n-(3-Hydroxypyridin-3-Yl)Pivalamide is a specialized organic compound featuring a pyridine core substituted with both a hydroxyl group and a pivalamide moiety. This unique molecular structure makes it a valuable pharmaceutical intermediate and research chemical for the synthesis of more complex active molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors seeking high-purity building blocks for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of compound libraries for biological screening.
• Chemical Synthesis: Serves as a precursor for the development of more complex heterocyclic compounds and functionalized pyridine derivatives.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.
• Material Science: Can be investigated as a monomer or ligand for creating specialized polymers or metal-organic frameworks (MOFs).

Basic Information

Product Name	n-(3-Hydroxypyridin-3-Yl)Pivalamide
CAS No.	177744-83-1
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	3-Hydroxy-N-(1,1-dimethylethyl)pyridine-2-carboxamide; 2-Pyridinecarboxamide, 3-hydroxy-N-(1,1-dimethylethyl)-; Pivalic acid (3-hydroxy-2-pyridyl)amide; N-(tert-Butyl)-3-hydroxypicolinamide; 3-Hydroxy-N-tert-butylpicolinamide; 3-Hydroxy-2-picolinoylt-butylamine; 3-Hydroxy-N-(3-hydroxy-2-pyridinyl)-2,2-dimethylpropanamide (related form)
EINECS	Contact for details

Quality Control

Our n-(3-Hydroxypyridin-3-Yl)Pivalamide is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality protocols are designed to meet the stringent requirements of pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.